Toxic Effects of Di-2-ethylhexyl Phthalate: An Overview Di-2-ethylhexyl phthalate (DEHP) is extensively used as a plasticizer in many products, especially medic
Get InquiryDi-2-ethylhexyl phthalate (DEHP) is extensively used as a plasticizer in many products, especially medical devices, furniture materials, cosmetics, and personal care products. DEHP is noncovalently bound to plastics, and therefore, it will leach out of these products after repeated use, heating, and/or cleaning of the products.
Quoted PriceBasis: Orally administered DEHP produced significant dose-related increases in liver tumor responses in rats and mice of both sexes. This may be a synopsis of the full weight-of-evidence narrative. Quantitative Estimate of Carcinogenic Risk from Oral Exposure (PDF) (14 pp, 121 K) Oral Slope Factor: 1.4 x 10 -2 per mg/kg-day.
Quoted PriceSubstance Name — Di(2-ethylhexyl)phthalate (DEHP) CASRN — 117-81-7 Primary Synonym — Bis(2-ethylhexyl)phthalate Last Revised — 01/31/1987 The oral Reference Dose (RfD) is based on the assumption that thresholds exist for certain toxic effects such as cellular necrosis. It is expressed in units of mg/kg-day. In general, the RfD is an
Quoted PriceDI (2-ETHYLHEXYL) PHTHALATE reacts with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing with alkali …
Quoted PriceMSDS Name: Dioctyl phthalate, 99+% Catalog Numbers: AC339140000, AC339140010, AC339140050 Synonyms: Di(2-ethylhexyl)phthalate; Di-sec-octyl phthalate; Bis(2-ethylhexyl)-1,2-benzenedicarboxylate; Bis(2-ethylhexyl)phthalate; DOP; Dioctyl phthalate; DEHP. Company Identification: Acros Organics N.V. One Reagent Lane Fair Lawn, NJ 07410
Quoted PriceThese phthalates include di(2-Ethylhexyl) phthalate (DEHP), di-n-octyl phthalate (DnOP), and di-iso-nonyl phthalate (DiNP), among others. DEHP is commonly used in medical products to impart flexibility to intravenous (IV) tubing, suction tubing, ventilation tubing, blood product containers, and infusion systems.
Quoted PriceBackground on Di-ethylhexyl Phthalate. Di-ethylhexyl phthalate is a colorless liquid at room temperature, most commonly used as a plasticizer. As reported to EPA during the 2016 Chemical Data Reporting (CDR) period and described here as a range to protect production volumes that were claimed as confidential business information (CBI), aggregate production volume of di-ethylhexyl phthalate in …
Quoted PriceDi(2-ethylhexyl)phthalate (DEHP) is also known as 1,2-benzenedicarboxylic acid bis(2-ethylhexyl)ester, bis(2-ethylhexyl) phthalate, and dioctyl phthalate (DOP). Physicochemical properties (1,2) [Conversion factor in air: 1 ppm = 1.59 mg/m3] Property Value Physical state Light-coloured, viscous liquid Melting point -46 °C (pour-point)
Quoted Pricedi- (2-ethylhexyl)phthalate. Molecular Formula CHO. Average mass 390.556 Da. Monoisotopic mass 390.277008 Da. ChemSpider ID 5414319. – 2 of 2 defined stereocentres.
Quoted PriceThe human population may be exposed to DEHP by swallowing it, for example in food, by breathing it in, and, to a much lesser extent, by skin contact. Risks are assessed by dividing worst-case exposures to the exposures at which no harmful effects were observed in animal studies. This gives the margin of safety (MOS).
Quoted PriceDi-2-ethylhexyl phthalate (DEHP) is the most common member of the class of phthalates, which are used as plasticizers in polymer products to make plastic flexible. DEHP is also called bis (2-ethylhexyl) phthalate or dioctyl phthalate (DOP).
Quoted PriceFor each chemical contaminant or substance considered, a lead institution prepared a health criteria document evaluating the risks for human health from exposure to the particular chemical in drinking-water.
Quoted PriceEnvironmental exposure DEHP is a component of many household items, including tablecloths, floor tiles, shower curtains, garden hoses, rainwear, dolls, toys, shoes, medical tubing, furniture upholstery, and swimming pool liners. [11] DEHP is an indoor air pollutant in homes and schools.
Quoted PriceDEHP, which is an abbreviation for di(2-ethylhexyl) phthalate, is a manufactured chemical that is commonly added to plastics to make them flexible. Other names for this compound are dioctyl phthalate (DOP) and bis(2-ethylhexyl) phthalate (BEHP). (Note that di-n-octyl phthalate, however, is the name for a different chemical.)
Quoted PriceDi(2-ethylhexyl) phthalate 1.3.1 Natural occurrence DEHP is not known to occur naturally. 1.3.2 Occupational exposure According to the 1981–83 National Occup
Quoted Pricefor specialist applications. The most commonly used phthalate esters (PEs) are di-2-ethylhexyl phthalate (DEHP) also referred to as DOP or DNOP (di-octyl phthalate), di-isodecyl phthalate (DIDP) and di-isononyl phthalate (DINP). PEs are clear liquids, with little or no smell and are of low volatility.
Quoted PriceB.1. LITERATURE SEARCH AND SCREEN. A literature search and screen was conducted to identify studies examining health effects, toxicokinetics, mechanisms of action, susceptible populations, biomarkers, chemical interactions, physical and chemical properties, production, use, environmental fate, environmental releases, and environmental and biological monitoring data for DEHP.
Quoted PriceDi(2-ethylhexyl) phthalate (DEHP) is a member of the phthalate ester chemical class that occurs commonly in the environment and to which humans are widely exposed. Lifetime exposure to DEHP is likely to occur, including during the in utero and early postnatal windows of development. To date, no carcinogenicity assessments of DEHP have used a lifetime exposure paradigm that includes the …
Quoted PriceWhat is DEHP? Di(2-ethylhexyl)phthalate (DEHP) is a man-made chemical. It is a colorless liquid with a slight odor. DEHP is added to plastics to make them flexible. It can be present in many common items such as wall coverings, floor tiles, upholstery, rainwear, packaging film and sheets, medical tubing, and blood storage bags.
Quoted PriceDi(2-ethylhexyl)phthalate, also known as DEHP, is an organic ester containing an eight-carbon alcohol moiety widely used as a plasticizer in polymers. DEHP is widely used for a variety of standard products due to its overall performance characteristics, including fusion rate, efficiency, and viscosity (Cadogan and Howick 2001; TURI 2006).
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